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Traumatic Brain Injury Pt 4

Traumatic Brain Injury, Pt. 4

Prognosis: Implications for Long-Term Recovery and Disability

The science of predicting long-term recovery and disability following TBI is anything but precise.Sometimes–for reasons not well understood—an individual with MTBI will develop permanent and profound disabilities while another person with a seemingly serious TBI will appear to recover fully. When most people think of TBI, they think of it as just that—an acute injury, something that they can eventually “get over”—as opposed to a disease with long-term sequelae. TBI, though, is formally recognized as a progressive disease involving injury to the neuronal cell bodies –the brain’s “gray matter”—and the axonal processes, the white matter controlling the biochemical and electrical conveyance of messages from one neuron to the next (http://www.tbims.org/combi).

Prognosis during the Early Stages of TBI

Understandably, patients with TBI and their families are anxious for a prognosis during the early stages of recovery. Clinicians are often reluctant to provide a definitive answer, especially since complications of TBI often do not emerge for months or even years following brain injury. (A contemporary example involves the retired football players who have filed suit against the NFL for injuries sustained 20-30 years prior leading to their development of CTE.) Nonetheless, a few early indicators of a poor prognosis include:

  • Duration of coma.
  • Severity of coma.
  • Duration of post-traumatic amnesia.
  • Location and  size of contusions and hemorrhages in the brain.
  • Severity of injuries to other body systems sustained at the time of TBI.

Other generalizations that can be shared are:

  • The more severe the injury, the longer the recovery period, and the greater the impairment once recovery has plateaued (sometimes a period of 2-3 years post-TBI).
  • Recovery from diffuse axonal injury takes longer than recovery from focal contusion.
  • Recovery from TBI with hypoxia (oxygen deprivation to the tissues) is less complete than TBI without hypoxia.
  • Need for surgery does not necessarily spell a worse outcome.
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